Exposición al alcohol fetal a través de ésteres etílicos de biomarcadores de ácidos grasos en meconio
DOI:
https://doi.org/10.11606/issn.1806-6976.smad.2023.190096Palabras clave:
Trastornos Relacionados con el Alcohol, Embarazo, MeconioResumen
Objetivo: identificar la evidencia en la literatura sobre métodos que cuantifiquen los biomarcadores
de exposición fetal al alcohol presentes en la matriz biológica de meconio: ésteres etílicos de
ácidos grasos (FAEE). Metodología: búsqueda realizada en tres bases de datos, utilizando las
expresiones fijas “éster de éster graso y meconio”. Se seleccionaron artículos publicados hasta
julio de 2018, cuyos participantes eran mujeres embarazadas que consumían o no alcohol y a
las que se les recogieron muestras de meconio de sus recién nacidos. Resultados: de las 201
referencias encontradas, 27 artículos cumplieron los criterios de inclusión, extrayendo datos de
los artículos seleccionados, tales como: método de prueba (análisis), método de extracción,
biomarcadores analizados, punto de corte, estándar interno y cantidad de meconio utilizado.
Conclusión: dentro de la variabilidad de los biomarcadores FAEEs, Etil Linoleato, Etil Palmitato,
Etil Estearato y Etil Oleato, fueron más prevalentes y en mayores concentraciones. La suma de
FAEE es más adecuada y confiable que el análisis individual.
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Derechos de autor 2023 SMAD, Revista Eletrônica Saúde Mental Álcool e Drogas (Edição em Português)
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
