Exercise in osteogenesis imperfecta

Abstract

Osteogenesis imperfecta (OI) is a genetic disorder of the connective tissue, characterized by bone fragility and low bone density, with a broad spectrum of clinical expression. Oriented physical exercise is recognized as a relevant conservative treatment option. Objective: To gather and systematize knowledge related to physical fitness testing, choosing exercises, load progression, and training systematization for persons with OI. Method: Databases from SciELO, LILACS, MedLine, Scopus, PubMed, Web of Science, PEDro and the Cochrane BVS were searched. Two independent reviewers selected the eligible studies. All randomized controlled clinical trials, transversal exploratory studies, case reports, and experience reports that described physical exercise intervention and physical fitness testing; general rules for physical activity and reported physical activity effects were included. Results: The electronic search yielded a total of 961 references published in English, Portuguese, French, and German. After analyzing previously established inclusion criteria, 9 studies were included, only two of which were controlled clinical trials. All the recommendations and conclusions found were oriented toward children, since all the studies had this population as a target. Only two studies included samples of adolescents up to the age of 12 years. OI types I and IV were investigated and some of the recommendations were extended to the other types of OI. Swimming is the exercise recommended most often. Strengthening exercises, with a slow addition of weight were also recommended, as well as aerobic exercises on bicycles, stationary or not. There are some special considerations in handling and treatment for this public that should be taken to avoid trauma. Conclusion: It was possible to obtain some systematization and orientation to conduct conservative treatment interventions with a physical exercise program; however, evidence to support any prescribed exercise and training development for persons with OI is still scarce.