Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez.

Authors

  • Natasha Tiemi Fabri Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products https://orcid.org/0000-0003-4237-7626
  • Larissa Junqueira Gatto Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products
  • Alethéia Santos Furusho Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products
  • Meira Janette Ballestros Garcia Federal University of Paraná, Chemistry Department, Laboratory of Chemical Ecology and Synthesis of Natural Products
  • Francisco de Assis Marques Federal University of Paraná, Chemistry Department, Laboratory of Chemical Ecology and Synthesis of Natural Products
  • Marilis Dallarmi Miguel Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products
  • Deise Prehs Montrucchio Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products
  • Sandra Maria Warumby Zanin Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products
  • Obdulio Gomes Miguel Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products https://orcid.org/0000-0002-2231-9130
  • Josiane de Fátima Gaspari Dias Federal University of Paraná, Pharmacy Department, Laboratory of Natural Products

DOI:

https://doi.org/10.1590/s2175-97902019000218471

Keywords:

Ocotea diospyrifolia, Lauraceae, Spathulenol, Antioxidant, Toxicity

Abstract

The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were δ-elemene, spathulenol, and β-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells.

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Published

2019-12-09

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Article

How to Cite

Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. (2019). Brazilian Journal of Pharmaceutical Sciences, 55, e18471 . https://doi.org/10.1590/s2175-97902019000218471