Chemical composition and larvicidal activity of the essential oil of Tagetes minuta Linnaeus from the southern Brazilian highlands

Elisiane de Bona  Sartor; Renan Reisdörfer  Schorr; Fernando Cesar Martins  Betim; Cintia Aparecida dos  Anjos; Camila Freitas de  Oliveira; Luciane  Dalarmi; Deise Prehs  Montrucchio; Josiane de Fátima Gaspari  Dias; Obdulio Gomes  Miguel; Marilis Dallarmi  Miguel

doi:10.1590/

Autores

Elisiane de Bona Sartor Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0003-4303-916X
Renan Reisdörfer Schorr Department of Chemistry, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0002-2695-5564
Fernando Cesar Martins Betim Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0002-1668-8626
Cintia Aparecida dos Anjos Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0001-5716-8646
Camila Freitas de Oliveira Departament of Farmacy, Unicentro University, Guarapuava, Brazil https://orcid.org/0000-0002-8549-5182
Luciane Dalarmi Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0001-8217-2487
Deise Prehs Montrucchio Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0003-1440-7007
Josiane de Fátima Gaspari Dias Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0002-8548-8505
Obdulio Gomes Miguel Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0002-2231-9130
Marilis Dallarmi Miguel Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Brazil https://orcid.org/0000-0002-1126-9211

DOI:

https://doi.org/10.1590/

Palavras-chave:

Tagetes minuta, Essential oil, Larvicidal, Brazilian highlands, Tagetone

Resumo

Tagetes minuta L. is a naturalized species that is not endemic to the high-altitude fields of Santa Catarina in southern Brazil. In this study, we investigated the composition of the essential oil (EO) from the flowers of the plant and its larvicidal activity against Aedes aegypti. The EO was obtained by hydrodistillation using a Clevenger apparatus. The chemical composition was determined using gas chromatography coupled with mass spectrometry (GC-MS). The EO extraction yield was 4.9%, and the major compounds (Z)-tagetone, (Z)-β-ocimene, and dihydrotagetone were identified. The 24 h larvicidal activity was verified against that of L3 larvae of the Rockefeller strain of Ae. Aegypti. The EO showed larvicidal activity against Ae. aegypti, with LC₅₀ = 17.28 μg/mL^-1. The results indicate that the bioinsecticidal potential of T. minuta EO is promising for the development of research in the field of natural products.

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Referências

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Chemical composition and larvicidal activity of the essential oil of Tagetes minuta Linnaeus from the southern Brazilian highlands

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