Mushroom tyrosinase inhibitory activity and major fatty acid constituents of Amazonian native flora oils

Authors

  • Raquel da Silva Teixeira Federal University of Juiz de Fora; NIQUA
  • Paula Rafaela Rocha Federal University of Juiz de Fora; NIQUA
  • Hudson Caetano Polonini Federal University of Juiz de Fora; NUPICS
  • Marcos Antônio Fernandes Brandão Federal University of Juiz de Fora; NUPICS
  • Maria das Graças Afonso Miranda Chaves Federal University of Juiz de Fora; NUPICS
  • Nádia Rezende Barbosa Raposo Federal University of Juiz de Fora; NUPICS

DOI:

https://doi.org/10.1590/S1984-82502012000300006

Keywords:

Amazonian plants^i1^sevaluat, Amazonian plants^i1^sdermatological, Skin lightening agents, Tyrosinase^i1^sinhibit, Tyrosinase^i1^sin vitro evaluat, Melanin, Hyperpigmentation^i1^streatm

Abstract

In order to treat hyperpigmentation-related problems, there has been a global trend in developing cosmetics claiming to have skin-whitening properties, which act by inhibiting melanin biosynthesis. The objective of this work was to evaluate the in vitro mushroom tyrosinase inhibitory activity of five Amazonian native flora oils, and so to verify the possibility of their incorporation into cosmetic products. In addition, the fatty acid composition of the essential oils was determined by gas chromatography-flame ionisation detection in order to determine the main components of these oils. The tyrosinase inhibitory activity of the tested oils was found to be in the following order: açaí (IA50 = 66.08 µg mL-1) >; tucumã >; patauá >; pracaxi >; castanha do Brasil. This study suggests that açaí oil has great potential in the treatment of hyperpigmentation and other related disorders, due to its considerable tyrosinase inhibitory activity.

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Published

2012-09-01

Issue

Vol. 48 No. 3 (2012)

Section

Articles

License

All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.

The on-line journal has open and free access.

How to Cite

Mushroom tyrosinase inhibitory activity and major fatty acid constituents of Amazonian native flora oils. (2012). Brazilian Journal of Pharmaceutical Sciences, 48(3), 399-404. https://doi.org/10.1590/S1984-82502012000300006