Use of Nile tilapia (Oreochromis niloticus) skin as a xenograft in the treatment of a sporotrichosis-induced wound in a feline: short communication
DOI:
https://doi.org/10.11606/issn.1678-4456.bjvras.2025.227998Keywords:
Felidae, Graf, Healing, WoundsAbstract
Sporotrichosis is a fungal infection often characterized by complications related to wound healing. This study was performed to evaluate the use of skin from Nile tilapia (Oreochromis niloticus) as a biological dressing in a sporotrichosisinduced wound in a feline. Amputation was initially indicated because of an extensive injury with bone necrosis in the distal third of the limb. To promote proper healing, the tissue (xenograft) was applied to the lesion, and the dressing was changed every 48 hr for 3 weeks. Histological analysis of tilapia skin revealed intact collagen fibers and preservation of cellular architecture. After complete healing, the animal’s skin and mobility were restored, improving its quality of life. This report demonstrates the applicability of tilapia skin as a xenograft for treating wounds in domestic animals, achieving satisfactory results in reducing dressing changes and shortening healing time.
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Alvarenga MOP, Bittencourt LO, Mendes PFS, Ribeiro JT, Lameira OA, Monteiro MC, Barboza CAG, Martins MD, Lima RR. Safety and effectiveness of copaiba oleoresin (C. reticulata Ducke) on inflammation and tissue repair of oral wounds in rats. Int J Mol Sci. 2020;21(10):3568. https://doi.org/10.3390/ijms21103568. PMid:32443593.
Alves APNN, Verde MEQL, Ferreira Júnior AEC, Silva PGB, Feitosa VP, Lima Júnior EM, Carvalho NBF. Microscopic evaluation, histochemical study, and analysis of tensile properties of Nile tilapia skin. Rev Bras Queim. 2015;14(3):203-10.
Barreira NKV, Santos CC, Tamehiro CY, Zacarias FGS, GrazianoCEPL, Zacarias JuniorA. Microbiological evaluation of skin of Nile tilapia (Oreochromis niloticus) stored after chemical decontamination for dressing dogs. Braz J Dev. 2022;8(7):51167-78. https://doi.org/10.34117/bjdv8n7-165.
Buote NJ. Updates in wound management and dressings. Vet Clin North Am Small Anim Pract. 2022;52(2):289-315. https://doi.org/10.1016/j.cvsm.2021.12.001. PMid:35082098.
Costa BO, Lima Júnior EM, Fechine FV, Nunes Alves APN, Oliveira de Melo MM, Correia Ribeiro WL, Araújo RF, Pinheiro ALB, Lima V. Treatment of a traumatic equine wound using Nile tilapia (Oreochromis niloticus) skin as a xenograft. Acta Sci Vet. 2020;48:99678. https://doi.org/10.22456/1679-9216.99678.
Elbialy ZI, AtibaA, AbdelnabyA, Al-Hawary II, Elsheshtawy A, El-Serehy HA, Ali SE, Morsy W, El-Banna R. Collagen extract obtained from Nile tilapia (Oreochromis niloticus) skin accelerates wound healing in rat model via upregulating VEGF, bFGF, and α-SMA gene expression. BMC Vet Res. 2020;16(1):449. https://doi.org/10.1186/s12917-020-02566-2.
Estevão LRM, Medeiros JP, Baratella-Evêncio L, Simões RS, Mendonça FS, Evêncio-Neto J. Effects of the topical administration of copaiba oil ointment (Copaifera langsdorffii) in skin flap viability of rats.Acta Cir Bras. 2013;28(12):863- 9. https://doi.org/10.1590/S0102-6502013001200009. PMid:24316860.
Lima-Junior EM, Picollo NS, Miranda MJB, Ribeiro WLC, Alves APNN, Ferreira GE, Parente EA, Moraes Filho MO. Use of Nile tilapia skin (Oreochromis niloticus) as a biological dressing for burn treatment. Rev Bras Queim. 2017;16(1):10-7.
Mann FA, Constantinescu GM, Yoon HY. Fundamentos de cirurgia em pequenos animais. 1. ed. Rio de Janeiro: Elsevier; 2014. Oliveira ALA. Cirurgia veterinária em pequenos animais. 1. ed. São Paulo: Manole; 2022.
Oliveira SHS, Soares MJGO, Rocha PS. Use of collagen and aloe vera dressings in the treatment of ischemic wounds: a case study. Rev Esc Enferm USP. 2010;44(2):346-51. https://doi.org/10.1590/S0080-62342010000200015. PMid:20642045.
Oryan A, Alemzadeh E, Moshiri A. Burn wound healing: present concepts, treatment strategies and future directions. J Wound Care. 2017;26(1):5-19. https://doi.org/10.12968/jowc.2017.26.1.5. PMid:28103165.
Paranhos SB, Ferreira EDS, Canelas CAA, Paz SPA, Passos MF, Costa CEF, Silva ACR, Monteiro SN, Candido VS. Chitosan membrane containing copaiba oil (Copaifera spp.) for skin wound treatment. Polymers. 2021;14(1):35. https://doi.org/10.3390/polym14010035. PMid:35012060.
Passini Y, Aiub PB. Uso de pele de tilápia (Oreochromis niloticus) em acidentes por queimadura em animais selvagens. Bol APAMVET. 2019;10(2):29-31.
Tillmann MT, Felix SR, Mundstock CP, Mucillo GB, Fernandes CG, Nobre MO. Tratamento e manejo de feridas cutâneas em cães e gatos: revisão de literatura. Nosso Clínico. 2015;18(103):12-20.
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