Primary biliary cirrhosis and myopathy: an uncommon association

Authors

  • Bruno Cupertino Migueletto University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Abrahão Elias Hallack Neto University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Elaine Zamora Domingues University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Pedro Paulo Neves de Castro University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Hartmut Stocker University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Sueli K. Nagahashi Marie University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Luiz Pedro Meireles University of São Paulo; School of Medicine; Department of Clinical Medicine
  • Milton Hideaki Arai University of São Paulo; School of Medicine; Department of Clinical Medicine

DOI:

https://doi.org/10.1590/S0041-87811999000500007

Keywords:

Primary biliary cirrho, Myopa

Abstract

Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the majority of cases, muscular weakness has been interpreted as polymyositis. We report the case of a 48-year-old woman suffering from classic PBC, in association with a myopathy whose histological features are distinct from the cases reported before. We also performed a MEDLINE research for PBC and concomitant muscular diseases.

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Published

1999-10-01

Issue

Section

Case Report

How to Cite

Migueletto, B. C., Hallack Neto, A. E., Domingues, E. Z., Castro, P. P. N. de, Stocker, H., Marie, S. K. N., Meireles, L. P., & Arai, M. H. (1999). Primary biliary cirrhosis and myopathy: an uncommon association . Revista Do Hospital Das Clínicas, 54(5), 165-168. https://doi.org/10.1590/S0041-87811999000500007