IMUNIDADE À DIFTERIA FRENTE À PROVA DE SCHICK E À DOSAGEM DE ANTITOXINA DIFTÉRICA CIRCULANTE

Authors

  • José da Silva Guedes Universidade de São Paulo
  • Luiz G. Cottilo Z. Universidad Mayor de San Marcos
  • Sebastião Timo Iaria
  • José Antonio Alves dos Santos
  • Geraldo Paulo Bourroul

DOI:

https://doi.org/10.11606/issn.2358-792X.v20i2p233-240

Abstract

Of the 95 second year medicai students of the F.C.M.S.C., 56 were suhmitted to the Schick test, which was performed on two occasions with 28 days interval hetween each one. Blood was drawn from the subjects on three occasions: before the first Schick test and seven and twenty-eight days after the said test. Diphtheria antitoxin was titrated in hlood by the passive hemagglutination test.In Schicknegative suhjects. hoth tests agreed in 94.1$, 97.1%, and 97% on first, serond and third titrations respectively. In Schkk-positive suhjects agreement was ohserved in 59,1%, 54,5% and 72%; for same titrations. Alterations of antitoxin leveis due to performance of the Schick test itself are discussed. Diphtheria antitoxin titration is recommended in adults and adolescenb which show susceptibility to the Schick test.

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Author Biographies

  • José da Silva Guedes, Universidade de São Paulo

    Assistente do Departamento de Medicina Social da F.C.M.S.C.; Instrutor de Medicina Preventiva da Faculdade de Medicina da Universidade de São PAulo

  • Luiz G. Cottilo Z., Universidad Mayor de San Marcos

    Instrutor da Cadeira de Microbiologia e Imunologia Aplicadas; Catedrático Auxiliar de Microbiologia - Facultad de Farmacia y Bioquimica, Universidad Mayor de San Marcos

  • Sebastião Timo Iaria
    Instrutor da Cadeira de Microbiologia e Imunologia Aplicadas
  • José Antonio Alves dos Santos
    Professor Assistente da Cadeira de Epidemiologia e Profilaxia Gerais e Especiais
  • Geraldo Paulo Bourroul

    Assistente do Departamento de Medicina Social da F.C.M.S.C.; Instrutor de Medicina Preventiva da Faculdade de Medicina da Universidade de São Paulo

Published

1966-12-28

Issue

Section

Não Definida

How to Cite

Guedes, J. da S., Cottilo Z., L. G., Iaria, S. T., Santos, J. A. A. dos, & Bourroul, G. P. (1966). IMUNIDADE À DIFTERIA FRENTE À PROVA DE SCHICK E À DOSAGEM DE ANTITOXINA DIFTÉRICA CIRCULANTE. Arquivos Da Faculdade De Higiene E Saúde Pública Da Universidade De São Paulo, 20(2), 233-240. https://doi.org/10.11606/issn.2358-792X.v20i2p233-240